
The Clarke Error Grid was used to assess the clinical relevance of the differences between the Guardian RT
readings and the comparative YSI measurements. The Clarke Error Grid divides a correlation plot into 5 zones.
See following table.
Results in zones A and B are considered clinically acceptable, while results in zones C, D, and E are potentially
dangerous and, therefore, clinically significant errors. The Clarke Error Grid zones are labeled on the
correlation plot.
Zone
Description
A Clinically accurate, would lead to correct treatment decisions
B Would lead to benign decisions or no treatment
C Would lead to over-correction of normal glucose levels
D Would lead to failure to detect and treat high or low glucose levels
E Would lead to erroneous treatment decisions
Appendix A
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